Its long been the stance of Luc Besson that his classic contract killer film The Professional would not be sequeled with him involved. The film starred a very young Natalie Portman who is now on record saying she would be up for a sequel, but only if Besson directs.

MTV says:

Years have passed, director Luc Besson has gone on record as refusing to helm a second installment, and nothing seems likely to change. Portman herself told us recently that she’s even declined to read the script.

“I have never read it because Luc won’t direct it himself, and so I’m only interested if he [directs],” she said while at the Toronto Film Festival promoting “Black Swan.”

I think that this would make a great story if they did sequel The Professional catching up with her character so much later, but I agree that Luc Besson should do it, and seeing as how he still says he won’t… it wont happen.

If they sequel it without the same cast or director? The Professional: Havana Nights